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Image Search Results
Journal: Bioengineered
Article Title: Silence of TANK-binding kinase 1 (TBK1) regulates extracellular matrix degradation of chondrocyte in osteoarthritis by janus kinase (JAK)-signal transducer of activators of transcription (STAT) signaling
doi: 10.1080/21655979.2021.2018976
Figure Lengend Snippet: Silencing of TBK1 inhibited ECM degradation in OA mice. ACLT mice were infected with lentivirus shTBK1 or shNC. (a) TBK1 mRNA level was detected by qRT-PCR. (b) Safranin O-fast green staining and (c) OARSI score were used for elevating cartilage destruction. (d) Serum CTX-II and (e) COMP were analyzed by the corresponding ELISA kits. * p < 0.05.
Article Snippet: The serum levels of cartilage metabolic markers, including C-terminal crosslinking telopeptide of
Techniques: Infection, Quantitative RT-PCR, Staining, Enzyme-linked Immunosorbent Assay